Search results for " Minimally invasive"

showing 10 items of 45 documents

The role of surgery in platinum-resistant ovarian cancer: A call to the scientific community.

2021

Abstract In the last decade, a growing attention has been focused on identifying effective therapeutic strategies also in the orphan clinical setting of women with platinum-resistant disease. In this context, secondary cytoreductive surgery (SCS) remains a potential approach only in women with platinum sensitive relapse, but experimental data have been published supporting the role of SCS also in patients with platinum-resistant recurrence. In particular, surgery is emerging as a potential option in specific subgroups of women, such as those patients with low-grade serous histology, or low-volume relapse with disease located in the so-called pharmacological sanctuaries. Furthermore, contras…

0301 basic medicineCancer Researchmedicine.medical_specialtymedicine.medical_treatmentContext (language use)Antineoplastic AgentsPlatinum CompoundsDiseaseHyperthermic Intraperitoneal ChemotherapyCarcinoma Ovarian Epithelial03 medical and health sciences0302 clinical medicineMedicineAnimalsHumansIn patientPlatinum resistantChemotherapybusiness.industryCytoreduction Surgical Proceduresmedicine.diseaseCombined Modality TherapySurgerySerous fluid030104 developmental biologyDrug Resistance Neoplasm030220 oncology & carcinogenesisPlatinum sensitiveFemaleNeoplasm Recurrence LocalbusinessOvarian cancerBiological features Minimally invasive surgery Personalized treatment Platinum resistant Recurrent ovarian cancer Secondary cytoreductive surgerySeminars in cancer biology
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How to select early-stage cervical cancer patients still suitable for laparoscopic radical hysterectomy: a propensity-matched study

2020

Background: Recently, it was reported that minimally invasive surgery (MIS) has a negative impact on early-stage cervical cancer (ECC) patient survival. At the same time, advantages of MIS regarding quality of life and low rate of intra- and postoperative complications are well known. Therefore, it is essential to select patients who may benefit from MIS without worsening their oncologic outcomes. The aim of this study is to investigate which pathological factors could guide surgeons’ choice about the best approach in ECC. Patients and Methods: Patients with 2009 FIGO stage from IA1 with lymphovascular space invasion (LVSI) to IB1/IIA1 treated by open or laparoscopic surgery were judged eli…

AdultLaparoscopic surgerymedicine.medical_specialtymedicine.medical_treatmentlaparoscopyUterine Cervical NeoplasmsHysterectomyDisease-Free Survivalopen surgeryYoung Adult03 medical and health sciences0302 clinical medicineSurgical oncologymedicineHumansMinimally Invasive Surgical ProceduresRadical HysterectomyPropensity ScoreLaparoscopyGrading (tumors)minimally invasive surgeryAgedNeoplasm StagingRetrospective StudiesAged 80 and overCervical cancermedicine.diagnostic_testbusiness.industryParametrialCervical cancer; laparoscopy; minimally invasive surgery; open surgery; radical hysterectomy; tumor diameterHazard ratioMiddle Agedmedicine.diseaseSurgerySurvival RateTreatment OutcomeSettore MED/40 - GINECOLOGIA E OSTETRICIAItalyOncology030220 oncology & carcinogenesisradical hysterectomyCervical cancerFemale030211 gastroenterology & hepatologySurgerytumor diameterbusiness
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Herpes Simplex I virus impairs regenerative outcomes of periodontal regenerative therapy in intrabony defects: a pilot study.

2011

Aim To evaluate the impact of herpesvirus type-1 and -2 on the clinical outcomes of periodontal regenerative procedures in isolated deep intrabony pockets, in an experimental population with no detectable periodontal pathogens. Materials and Methods Seventeen periodontal intraosseous defects in 17 moderate-to-advanced periodontitis patients were treated with regenerative therapy and amelogenins. Microbiological evaluation was performed at baseline (after the completion of initial therapy) and at 1 year to exclude the presence of periodontal pathogens. Herpesviruses-1 and -2 DNA were quantified in the pocket tissues associated to the intrabony defect using molecular assays. Clinical attachme…

AdultMaleBone RegenerationCONTROLLED CLINICAL-TRIALHerpesvirus 2 HumanHEALING RESPONSEPopulationAlveolar Bone LossDentistryHerpesvirus 1 HumanACCESS FLAPStatistics NonparametricYoung AdultDental Enamel ProteinsEnamel matrix derivativemedicineAggressive periodontitisHumansPeriodontal PocketGingival RecessionYoung adulteducationBone regenerationGingival recessionGUIDED TISSUE REGENERATIONBONY DEFECTSPeriodontitiseducation.field_of_studybusiness.industryAGGRESSIVE PERIODONTITISMiddle Agedmedicine.diseaseMICROBIOTAHUMAN HERPESVIRUSESPREVALENCEGUIDED TISSUE REGENERATION MINIMALLY INVASIVE SURGICAL TECHNIQUE CONTROLLED CLINICAL-TRIAL AGGRESSIVE PERIODONTITIS HUMAN HERPESVIRUSES HEALING RESPONSE BONY DEFECTS ACCESS FLAP PREVALENCE MICROBIOTAReal-time polymerase chain reactionTreatment OutcomeChronic PeriodontitisDNA ViralGuided Tissue Regeneration PeriodontalPeriodonticsFemaleMINIMALLY INVASIVE SURGICAL TECHNIQUEmedicine.symptombusinessJournal of clinical periodontology
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Minimally invasive video-assisted thyroidectomy: four-year experience of a single team in a General Surgery Unit.

2013

Minimally invasive video-assisted thyroidectomy (MIVAT) is a surgical technique that has showed increasingly good results, particularly in endocrine surgery centers. The aim of this prospective, non-randomized study was to evaluate feasibility, advantages and critical aspects of MIVAT in a general surgery unit.Two hundred twenty-four patients underwent total thyroidectomy for benign thyroid disease from May, 2008 to April, 2011. They were divided into two groups: one underwent conventional thyroidectomy (CT), and the other underwent MIVAT. The inclusion criteria were thyroid volume ≤35 mL and main nodule size ≤35 mm. For each patient, socio-demographic variables, hospitalization data and ou…

AdultMalePain PostoperativeTime FactorsVideo-Assisted SurgeryMiddle AgedSettore MED/45 - Scienze Infermieristiche Generali Cliniche E Pediatrichethyroidectomy minimally invasiveSettore MED/18 - Chirurgia GeneraleGeneral SurgeryThyroidectomyHumansMinimally Invasive Surgical ProceduresFemaleProspective StudiesSurgery Department Hospital
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Clinical analysis following lumbar interspinous devices implant: where we are and where we go

2014

Objectives:We present our experience with patients treated with interspinous devices who are affected by neurogenic intermittent claudication (NIC) or lumbar disc herniation (LDH) where the interspinous system has been inserted following microdiscectomy.Study design:Retrospective study.Methods:This study included patients (n=100) with NIC secondary to lumbar spinal stenosis (group 1), and patients (n=100) with LDH (group 2) in whom the interspinous device has been implanted following radicular decompression in a period spanning 6 years. The latter have been compared with a homogenous group of patients (n=100) where no interspinous system has been implanted following microdiscectomy (group 3…

AdultMaleReoperationMicrosurgerymedicine.medical_specialtyTime FactorsVisual analogue scaleDecompressionlumbar interspinous devicesAdult Prostheses and Implants Aged Decompression Surgical Disability Evaluation Female Follow-Up Studies Intermittent Claudication Intervertebral Disc Displacement Humans Lumbar Vertebrae Microsurgery Minimally Invasive Surgical Procedures Middle Aged Male Retrospective Studies Pain Measurement Patient Satisfaction Surveys and Questionnaires Reoperation Recurrence Treatment Outcome Spinal StenosisDisability EvaluationSpinal StenosisLumbarRecurrenceSurveys and QuestionnairesmedicineHumansMinimally Invasive Surgical ProceduresAgedPain MeasurementRetrospective StudiesLumbar VertebraeSettore MED/27 - Neurochirurgiabusiness.industryLumbar spinal stenosisProstheses and ImplantsGeneral MedicineIntermittent ClaudicationMiddle AgedDecompression Surgicalmedicine.diseaseIntermittent claudicationOswestry Disability IndexSurgeryTreatment OutcomeNeurologyPatient SatisfactionFemaleNeurology (clinical)Implantmedicine.symptombusinessClaudicationIntervertebral Disc DisplacementFollow-Up StudiesSpinal Cord
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Minimally Invasive Pelvic Exenteration for Gynecologic Malignancies: A Multi-Institutional Case Series and Review of the Literature.

2019

ABSTRACT Study Objective To assess the feasibility and efficacy of minimally invasive pelvic exenteration (MIPE) in a multi-institutional Italian case series of women with gynecologic cancer and a review of the literature. Design Retrospective cohort study (Canadian Task Force classification II-2). Setting Three Italian university/teaching hospitals: “Agostino Gemelli” Foundation University Hospital in Rome, "ARNAS Civico Di Cristina Benfratelli” Hospital in Palermo, and “Maggiore della Carita” Hospital in Novara. Patients We reviewed all consecutive cases with gynecologic malignancies in this multi-institutional setting recorded between March 2014 and June 2017. Women with primary or centr…

Adultmedicine.medical_specialtySurvivalGenital Neoplasms FemaleSurgical complicationsmedicine.medical_treatmentTumor resectionLaparoscopic pelvic exenteration; Minimally invasive pelvic exenteration; Robotic pelvic exenteration; Surgical complications; Survival03 medical and health sciences0302 clinical medicineSurgical complicationmedicineRecurrent diseaseLaparoscopic pelvic exenterationHumansMinimally Invasive Surgical ProceduresLaparoscopyAgedRetrospective Studies030219 obstetrics & reproductive medicinePelvic exenterationmedicine.diagnostic_testbusiness.industryGeneral surgeryRobotic pelvic exenterationObstetrics and GynecologyRetrospective cohort studyPerioperativeCytoreduction Surgical ProceduresMiddle AgedPelvic ExenterationLaparoscopic pelvic exenteration Minimally invasive pelvic exenteration Robotic pelvic exenteration Surgical complications Survival Obstetrics and GynecologySettore MED/40 - GINECOLOGIA E OSTETRICIAMinimally invasive pelvic exenteration030220 oncology & carcinogenesisOperative timeFemaleElectronic databasebusinessJournal of minimally invasive gynecology
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Laparoscopic Management of Ovarian Cancer Patients With Localized Carcinomatosis and Lymph Node Metastases: Results of a Retrospective Multi-institut…

2016

Abstract Study Objective To investigate the feasibility and safety of laparoscopic cytoreduction in ovarian cancer patients with localized carcinomatosis or lymph node involvement. Design Retrospective cohort study (Canadian Task Force classification II-2). Setting Multi-institutional study performed in 6 referral gynecologic oncology units. Patients Between June 2005 and December 2014, preoperatively presumed early-stage ovarian cancer patients, who accidentally revealed localized carcinomatosis or lymph node involvement at laparoscopic evaluation or at postoperative pathological examination managed by the laparoscopic approach. Interventions All patients with limited carcinomatosis and/or…

Adultmedicine.medical_specialtymedicine.medical_treatmentLaparoscopic cytoreduction; Laparoscopy; Minimally invasive surgery; Ovarian cancer; Adult; Aged; Aged 80 and over; Carcinoma; Cytoreduction Surgical Procedures; Disease-Free Survival; Feasibility Studies; Female; Humans; Laparoscopy; Lymph Nodes; Lymphatic Metastasis; Middle Aged; Neoplasm Recurrence Local; Ovarian Neoplasms; Retrospective Studies; Young AdultGynecologic oncologyDisease-Free SurvivalLaparoscopic cytoreduction Laparoscopy Minimally invasive surgery Ovarian cancerYoung Adult03 medical and health sciences0302 clinical medicineMinimally invasive surgeryOvarian cancerCytoreduction Surgical Procedures80 and overmedicineCarcinomaHumansLymph nodeSurvival rateAgedRetrospective StudiesAged 80 and overOvarian Neoplasms030219 obstetrics & reproductive medicinebusiness.industryCarcinomaObstetrics and GynecologyRetrospective cohort studyCytoreduction Surgical ProceduresMiddle Agedmedicine.diseaseSurgeryNeoplasm Recurrencemedicine.anatomical_structureLocalLaparoscopic cytoreductionLymphatic Metastasis030220 oncology & carcinogenesisFeasibility StudiesFemaleLaparoscopyLymphadenectomyLymph NodesNeoplasm Recurrence LocalbusinessOvarian cancerJournal of Minimally Invasive Gynecology
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Minimally invasive aortic valve surgery

2016

Aortic valve disease is a prevalent disorder that affects approximately 2% of the general adult population. Surgical aortic valve replacement is the gold standard treatment for symptomatic patients. This treatment has demonstrably proven to be both safe and effective. Over the last few decades, in an attempt to reduce surgical trauma, different minimally invasive approaches for aortic valve replacement have been developed and are now being increasingly utilized. A narrative review of the literature was carried out to describe the surgical techniques for minimally invasive aortic valve surgery and report the results from different experienced centers. Minimally invasive aortic valve replacem…

Aortic valve stenosiSymposium: Transcatheter aortic valve implantationOutcomesGeriatrics and GerontologyAortic valve stenosisMinimally invasiveCardiology and Cardiovascular MedicineAortic valve replacement; Aortic valve stenosis; Minimally invasive; Outcomes; Cardiology and Cardiovascular Medicine; Geriatrics and GerontologyOutcomeAortic valve replacement
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The role of minimal access valve surgery in the elderly. A meta-analysis of observational studies

2016

Background Minimal access valve surgery, both mitral and aortic, may be related to improvement in specific post-operative outcomes, therefore may be beneficial for the subgroup of the elderly referred for valve surgery. Methods A systematic literature review identified several different studies, of which 6 fulfilled criteria for meta-analysis. Outcomes for a total of 1347 patients (675 conventional standard sternotomy and 672 minimally invasive valve surgery) were assessed with a meta-analysis using random effects modeling. Heterogeneity, subgroup analysis with quality scoring were also assessed. The primary endpoint was early mortality. Secondary endpoints included intra and post-operative…

Aortic valvemedicine.medical_specialtymedicine.medical_treatmentSubgroup analysisContext (language use)030204 cardiovascular system & hematologylaw.invention03 medical and health sciences0302 clinical medicineMinimally invasive surgerylawMitral valvemedicineClinical endpointCardiopulmonary bypassHumansMinimally Invasive Surgical ProceduresIntubationMeta-analysiAortic valve; Meta-analysis; Minimally invasive surgery; Mitral valve; Statistics; SurgeryCardiac Surgical ProceduresStatisticAgedAged 80 and overCardiopulmonary BypassModels Statisticalbusiness.industryAge FactorsGeneral MedicineSurgeryObservational Studies as TopicTreatment Outcomemedicine.anatomical_structure030228 respiratory systemAortic ValveMeta-analysisAnesthesiaMitral ValveSurgerybusinessInternational Journal of Surgery
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Customized approach for otogenic brain abscess: the neurosurgical prospective.

2017

Bone Screws Decompression Surgical Humans Minimally Invasive Surgical Procedures Lumbosacral Region Neurosurgical Procedures Spinal Stenosis
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